Magento vs Dentrix Marketplace vs Henry Schein One vs Shopify for dental supply ecommerce?

Honest cut, distributor-specific:

• Dentrix Marketplace, clinic-side ordering inside the practice-management system. You don’t run a Dentrix Marketplace store; you get listed in it as a vendor. Good for reach into ~40% of US clinics that run Dentrix, but you don’t own the storefront, the customer relationship, or the data.
• Henry Schein One, Henry Schein’s vertical platform for dental practices. Same dynamic, you’re a vendor, not a platform owner. Worth being on, never enough on its own.
• Shopify, fine for direct-to-consumer dental brands selling whitening kits, electric brushes, and aligner aftercare. Hits ceilings hard for B2B distributors: 100 variants per product (Plus: 2,000), thin B2B layer, no native EDI, no FDA UDI / DSCSA workflow, no HIPAA-grade audit log. Migration trigger is usually $3M, $5M GMV with a growing DSO book.
• Magento (Open Source or Adobe Commerce), the right platform for a B2B dental supply distributor at any scale above a side-business. Owns the storefront, integrates to practice-management systems via REST/SOAP, handles 25k+ SKUs cleanly, native B2B Companies module for DSO accounts, EDI bridges to distributors and clinics, audit-defensible HIPAA layer.

Pattern most distributors land on: Magento as the platform of record, Dentrix Marketplace + Henry Schein One + Amazon Business as channels. Magento pushes feeds out, ingests orders back, owns customer data, runs auto-ship + Net-30.